In medical terms, stress is a physical or psychological stimulus that can produce mental or physiological reactions that may lead to illness. Technically speaking, stress is a disruption of homeostasis, which may be triggered by alarming experiences, either real or imaginary. The definition and much of the initial research on stress was completed by Austro-Canadian endocrinologist Hans Selye.

Mental responses to stress include adaptive stress (eustress), anxiety, and depression. Where stress enhances function (physical or mental) it may be considered good stress. However, if stress persists and is of excessive degree, it eventually leads to a need for resolution, which may lead either to anxious (escape) or depressive (withdrawal) behavior.

One may further appreciate from that definition that stress may derive from imagined experiences such as frightening movies. Further, the fulcrum of stress response is the presence of disparity between experience (real or imagined) and personal expectations. A person living in a fashion consistent with personally-accepted expectations has no stress even if the conditions might be interpreted as adverse from some outside perspective — rural people may live in comparative poverty, and yet be unstressed if there is a sufficiency according to their expectations. Finally, when there is chronic disparity between experience and expectations, stress may be relieved by acceptance. However, since acceptance is rarely complete except in children, stress resolution by this approach is also rarely complete. It has been said that stress is often a reaction to a crisis of predictability, that the mind is solely an instrument of prediction, and that the body may be divided into a vegetative process and an integrative process.

 
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